AROVI© | ENOXAPARIN 2000 IU

AROVI© is indicated in adults for: 

• Prophylaxis of venous thromboembolic disease in moderate and high risk surgical patients, in particular those undergoing orthopaedic or general surgery including cancer surgery. 
• Prophylaxis of venous thromboembolic disease in medical patients with an acute illness (such as acute heart failure, respiratory insufficiency, severe infections or rheumatic diseases) and reduced mobility at increased risk of venous thromboembolism. 
• Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), excluding PE likely to require thrombolytic therapy or surgery. 
• Prevention of thrombus formation in extra corporeal circulation during haemodialysis. 
• Acute coronary syndrome: 
• Treatment of unstable angina and Non ST-segment elevation myocardial infarction (NSTEMI), in combination with oral acetylsalicylic acid. 
• Treatment of acute ST-segment elevation myocardial infarction (STEMI) including patients to be managed medically or with subsequent percutaneous coronary intervention (PCI). 

Pharmacotherapeutic group: Antithrombotic agent, heparin group 

Arovi© works in two ways. 

• Stopping existing blood clots from getting any bigger. This helps your body to break them down and stops them from causing you harm. 
• Stopping blood clots from forming in your blood. 

Please refer to the instructions on the prescription established by your medical doctor. 

1.Treating blood clots that are in your blood 

• The usual dose is 150 IU (1.5 mg) for every kilogram of your weight each day or 100 IU (1 mg) for every kilogram of your weight twice a day. 
•  Your doctor will decide how long you should receive Arovi. 

2. Stopping blood clots forming in your blood in the following situations: 

• Operation or periods of limited mobility due to an illness 
• The dose will depend on how likely you are to develop a clot. You will be given 2,000 IU (20 mg) or 4,000 IU (40 mg) of Arovi each day. 
• If you are going to have an operation your first injection will be usually given 2 hours or 12 hours before your operation. 
• If you have restricted mobility due to illness, you will normally be given 4,000 IU (40 mg) of Arovi each day. 
• Your doctor will decide how long you should receive Arovi. 
• After you have had a heart attack 

Arovi can be used for two different types of heart attack called STEMI (ST segment elevation myocardial infarction) or Non STEMI (NSTEMI). The amount of Arovi given to you will depend on your age and the kind of heart attack you have had. 

NSTEMI type of heart attack: 

• The usual dose is 100 IU (1 mg) for every kilogram of weight every 12 hours. 
• Your doctor will normally ask you to take aspirin (acetylsalicylic acid) as well. 
• Your doctor will decide how long you should receive Arovi. 

STEMI type of heart attack if you are under 75 years old: 

• An initial dose of 3,000 IU (30 mg) of Arovi will be given as injection into your vein. 
• At the same time you will also be given Arovi as an injection underneath your skin (subcutaneous injection). The usual dose is 100 IU (1 mg) for every kilogram of your weight, every 12 hours. 
• Your doctor will normally ask you to take aspirin (acetylsalicylic acid) as well. 
• Your doctor will decide how long you should receive Arovi. 

STEMI type of heart attack if you are 75 years old or older: 

• The usual dose is 75 IU (0.75 mg) for every kilogram of your weight, every 12 hours. 
• The maximum amount of Arovi given for the first two injections is 7,500 IU (75mg). 
• Your doctor will decide how long you should receive Arovi. 

For patients that have an operation called percutaneous coronary intervention (PCI): 

Depending on when you were last given Arovi, your doctor may decide to give an additional dose of Arovi before a PCI operation. This is by injection into your vein. 

3. Stopping blood clots from forming in the tubes of your dialysis machine 

• The usual dose is 100 IU (1 mg) for every kilogram of your weight. 
• Arovi is added to the tube leaving the body (arterial line) at the start of the 

dialysis session. This amount is usually enough for a 4-hour session. However, your doctor may give you a further dose of 50 IU to 100 IU (0.5 to 1 mg) for every kilogram of your weight, if necessary. 

Instructions for use of the syringe: Please refer to the Patient Information Leaflet provided above for detailed information.